You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT ARCHIVES
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 134 No. 8, August 1980 TABLE OF CONTENTS
  Archives
  •  Online Features
  Letters to the Editor
 This Article
 •References
 •Full text PDF
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal
 Social Bookmarking
  Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit Add to Technorati Add to Twitter What's this?

Copper Ligands in Human Milk: A Vehicle for Copper Supplementation in the Treatment of Menkes' Disease?

BO LöNNERDAL, PHD; CARL L. KEEN, PHD; BRUCE HOFFMAN; LUCILLE S. HURLEY, PHD
Department of Nutrition University of California Davis, CA 95616

Am J Dis Child. 1980;134(8):802-803.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

To the Editor.—Recent results from our laboratory have shown that human milk, unlike cow's milk, contains a low-molecular-weight (LMW) zinc complex,1 now identified as zinc citrate.2 We have therefore hypothesized that the therapeutic value of human milk in the treatment of acrodermatitis enteropathica (AE), a genetic disorder of zinc metabolism, is due to the presence of this complex, which is thought to be highly available for absorption.3,4

Assuming that human milk may contain LMW copper as well as zinc complexes, Williams et al5 have suggested that human milk may also be of therapeutic value in the treatment of Menkes' kinky hair disease, a sexlinked genetic disorder in humans that is manifested by abnormal intestinal copper absorption and many characteristics similar to those of copper-deficient animals.6 Despite the aggressive use of copper in infants with Menkes' disease, the prognosis for these patients has not improved. . . . [Full Text PDF of this Article]



Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter     What's this?





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1980 American Medical Association. All Rights Reserved.