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Idiopathic (Pseudoidiopathic?) Hypoparathyroidism
HILLEL I. HOCHMAN, MD
Am J Dis Child. 1979;133(4):435-436.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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A boy with hypoparathyroid manifestations had adequate renal and skeletal responses to injected parathyroid extract but normal serum immunoreactive parathyroid hormone (i = PTH) concentrations. Low urinary cyclic adenosine monophosphate (c-AMP) excretion during hypocalcemia supported the clinical impression of parathyroid insufficiency.
Report of a Case.—A 16-year-old, mildly retarded boy had generalized seizures preceded by behavioral change and irritability of four-week duration. History indicated neonatal seizures with transient hypocalcemia and subdural hematoma. Additional convulsive episodes occurred in infancy and at 6 years of age, at which time serum calcium and phosphorus concentrations were normal on two occasions. Anticonvulsant therapy was given until the age of 8 years. His diet was well balanced and contained copious amounts of milk. Family history was unremarkable.
Physical examination on admission to the hospital showed a stuporous, tall, obese adolescent with bilateral papilledema and positive Chvostek's and Trousseau's signs. Skeletal or ectodermal signs of pseudohypoparathyroidism
. . . [Full Text PDF of this Article]
Author Affiliations
Department of Pediatrics Boston City Hospital Boston University School of Medicine 818 Harrison Ave Boston, MA 02118
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