This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Recommendations for Prospective Studies in Man

William R. Beisel, MD

Am J Dis Child. 1975;129(5):571-574.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Certain infections in the pregnant woman may be accompanied by deleterious effects on the fetus, regardless of the presence of fetal infection. Severe maternal infection can lead to fetal death in utero or to premature labor; less severe infections in the mother seem to be involved in the pathogenesis of fetal growth retardation.

The Figure is a set-theory diagram to illustrate a basic mechanistic concept, that various normal nutritional, biochemical, metabolic, or endocrine processes in the mother may be altered during states of infection or pregnancy. Individual maternal processes (illustrated by capital letters in the several sets) may be enhanced or suppressed as a typical physiologic response to pregnancy (lower middle set) or may remain unaltered. Infection (top middle set) initiates many specific responses in the host. In a pregnant woman, individual maternal processes may remain unchanged or may exhibit synergistic, antagonistic, or noncorrelating responses to the combination of both . . . [Full Text PDF of this Article]

Author Affiliations
From US Army Medical Research, Institute of Infectious Diseases, Fort Detrick, Frederick, Md.

Footnotes
Reprint requests to US Army Medical Research, Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21701 (Dr. Beisel).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?