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Jean-Pierre Soulier, MD; Charles Blatix; A. M. Courouce; D. Benamon; P. Amouch; J. Drouet

Am J Dis Child. 1972;123(4):429-434.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Traditional preventive measures against virus B hepatitis (SH, MS-2), new measures based on the detection of the Australia (Au) antigen, and some recent attempts at active and passive immunization against Au antigen will be discussed.

Traditional Preventive Measures

Traditional preventive measures are directed toward reducing contamination. Whole blood, red blood cell, and platelet concentrates, and especially plasma and certain derivatives of plasma, such as fibrinogen and cryoconcentrates are potential sources of contamination. Human plasma fraction (PPSB)¹ appears to be less susceptible to contamination than other preparations among prothrombin complex and factor IX concentrates. The size of the pool is important for plasma and derivatives.

Equipment for injection should be disposable. Needles, scalpels, if reused, and dental instruments should be sterilized with prolonged boiling or autoclaving. Sodium hypochloride, β-propiolactone, and ultraviolet light are usually used for disinfection. Crowding and poor sanitary conditions favor contamination since virus B may be transmitted . . . [Full Text PDF of this Article]

Author Affiliations
Paris

From the Centre National de Transfusion Sanguine, Paris.

Footnotes
Reprint requests to Centre National de Transfusion Sanguine, 6, rue Alexandre-Cabanel, 75 Paris 15 (Dr. Soulier).

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