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John E. Ott, MD; Arthur Robinson, MD

Am J Dis Child. 1969;117(3):357-368.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

SINCE Sotos et al¹ described the syndrome of cerebral gigantism characterized by large stature, typical facies, nonprogressive neurological disorder, and mental retardation, there have been 33 cases reported.^2-10 The purpose of this paper is to present an additional case report which includes some studies not previously emphasized, and to review the literature.

Report of a Case

The patient is an 11-year-old white girl who has been evaluated annually since her fifth year because of her large stature. Following a term pregnancy complicated by hyperemesis gravidarum, vaginal bleeding, marked edema, and a difficult six-hour labor, normal deliver ensued. There were no neonatal difficulties except moderate jaundice which persisted for one month. At birth, her measurements were as follows: length, 56 cm (22 inches) (> 97th percentile); weight, 4,423 gm (9 lb 12 ounces) (> 97th percentile); and head circumference, 40 cm (> 97th percentile).

General development was within normal . . . [Full Text PDF of this Article]

Author Affiliations
Denver

From the departments of pediatrics (Dr. Ott) and biophysics (Dr. Robinson), University of Colorado Medical Center, Denver.

Footnotes
Received for publication May 9, 1968.

Reprint requests to Department of Biophysics, University of Colorado Medical Center, 4200 E Ninth Ave, Denver 80220 (Dr. Robinson).

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