 |
|
Plasma Growth Hormone Responses and Growth Retardation of Hypothyroidism
Margaret H. MacGillivray, MD;
Thomas Aceto, Jr., MD;
Lawrence A. Frohman, MD
Am J Dis Child. 1968;115(2):273-276.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
|
|
|
RETARDED linear growth in hypothyroidism has been attributed to three causes: (1) secondary hypopituitarism with decreased growth hormone (GH) secretion; (2) reduced sensitivity of peripheral tissues to GH; and (3) fall in the caloric intake.1 Shiekholislam et al2 have reported abnormally low levels of plasma GH in seven of ten hypothyroid children after stimulation with insulin hypoglycemia. The children with impaired GH responses were subsequently restudied when they were euthyroid and experiencing normal growth. Their GH responses to hypoglycemia were then found to be normal.
This article is concerned with the results of serial evaluations of plasma GH responses in eight children with hypothyroidism. The study was designed to determine whether GH responsiveness estimated by established stimuli becomes normal prior to, concurrent with, or after the clinical and growth improvements which accompany thyroid replacement. Therefore, GH responses, growth rates, thyroid hormone levels, and bone maturation were assessed
. . . [Full Text PDF of this Article]
Author Affiliations
Buffalo
From the departments of pediatrics and medicine, State University of New York at Buffalo School of Medicine, Buffalo.
Footnotes
Received for publication Sept 18, 1967.
Read before the International Symposium on Growth Hormone, Sept 11-13, 1967, Milan, Italy.
Submitted by the authors for the Mitchell I. Rubin Festschrift issue of the Journal.
Reprint requests to 219 Bryant St, Buffalo 14222 (Dr. MacGillivray).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
|
