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Leticia U. Tina, MD; James B. D'Albora, MD; Tatiana T. Antonovych, MD; Joseph A. Bellanti, MD; Philip L. Calcagno, MD

Am J Dis Child. 1968;115(1):29-36.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

THE association of acute glomerulonephritis with a previous streptococcal infection is well known.^1-6 A reduction of serum hemolytic complement in various forms of nephritis has been adequately documented.^7-15 Measurement of serum β₁C-globulin levels have directly paralleled the serum hemolytic complement activity and, therefore, the serum β₁C-globulin level may be used as an indication of the serum complement activity.¹¹ There exists a preponderance of evidence which indicates that β₁C-globulin levels are low in acute glomerulonephritis, and exceptions to this established fact have been noted only in rare instances.^12,13

This report will present pertinent clinical, pathologic, and immunologic data in a group of children observed, during the winter months from 1962 to 1963 in the greater Washington, DC area,¹⁴ to have acute glomerulonephritis and in which a significant number failed to show a low β₁C-globulin level.

Methods and Clinical Material

Twenty-five children with the clinical features of acute glomerulonephritis, hospitalized on the . . . [Full Text PDF of this Article]

Author Affiliations
Washington, DC

From the departments of pediatrics, pathology and microbiology of Georgetown University School of Medicine, Children's Hospital of DC, Arlington Hospital, Arlington, Va, and Georgetown University Hospital.

Footnotes
Received for publication Oct 31, 1966.

Reprint requests to Georgetown University Hospital, 3800 Reservoir Rd, NW, Washington, DC 20007 (Dr. Calcagno).

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