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  Vol. 113 No. 6, June 1967 TABLE OF CONTENTS
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Reversible Secondary Disaccharidase Deficiency

J. D. Welsh, MD; M. G. Porter, MD

Am J Dis Child. 1967;113(6):716-720.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

DIETARY disaccharides are hydrolyzed by specific enzymes in the brush border membrane of the small intestinal surface epithelial cells.1 Disaccharide malabsorption may be primary and result from the congenital or acquired absence of a specific functional element of the digestive-absorptive surface or may be secondary and caused by a reduction in the total available digestive-absorptive surface, as a consequence of other disease.2 Young children whose initial symptoms are consistent with gastroenteritis may develop a temporary secondary disaccharidase deficiency associated with intestinal mucosal damage.3 This report will present such a patient and discuss the confusion that may arise in diagnosis, if complete studies are not performed.

Methods

Oral carbohydrate-tolerance tests were performed in a uniform fashion using 2 gm of sugar per kilogram of body weight. The blood sugar was determined in duplicate by the Nelson-Somogyi method4 on samples obtained from the fasting patient and at one-half . . . [Full Text PDF of this Article]


Author Affiliations



Oklahoma City

From the departments of medicine (Dr. Welsh) and pediatrics (Dr. Porter), University of Oklahoma Medical Center, Oklahoma City.


Footnotes



Received for publication Sept 30, 1966.

Reprint requests to Department of Medicine, University of Oklahoma Medical Center, 800 NE 13th St, Oklahoma City 73104 (Dr. Welsh).



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