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Complement-Fixation, Hemagglutination-Inhibition And Intradermal Skin Tests for Mumps in Children With and Without Endocardial Fibroelastosis

JOHN B. VOSBURGH, MD; ANTONI M. DIEHL, MD; CHIEN LIU, MD; RONALD M. LAUER, MD; AKINYELE FABIYI, PhD

Am J Dis Child. 1965;109(1):69-73.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

PRIMARY ENDOCARDIAL fibroelastosis has been recognized as a distinct entity characterized by endocardial thickening involving either or both left and right sides of the heart. It is unassociated with other cardiac anomalies and usually occurs in infancy. Recent investigations^1-6 have emphasized the clinical features of this disease in infants, thus facilitating an accurate antemortem diagnosis and institution of therapy.

The hypothesis that the endocardial thickening is a manifestation of an intrauterine infection has been revived recently by Noren et al.⁷ These investigators demonstrated the presence of a positive reaction to mumps antigen injected intradermally in all of nine children with a clinical diagnosis of endocardial fibroelastosis. There was a history of exposure to mumps in two of the mothers and clinical mumps was present during the first trimester of pregnancy in another of the nine mothers. Noren concluded that intrauterine infection with the mumps virus in the first . . . [Full Text PDF of this Article]

Author Affiliations
KANSAS CITY, KAN

From the departments of pediatrics and medicine, University of Kansas School of Medicine. Intern (Dr. Vosburgh), Associate Professor of Pediatrics (Dr. Diehl), Professor of Pediatrics and Medicine (Dr. Liu), Assistant Professor of Pediatrics (Dr. Lauer and Dr. Fabiyi), University of Kansas School of Medicine.

Footnotes
Received for publication July 6, 1964.

Reprint requests to Rainbow Blvd at 39th St, Kansas City, Kan 66103 (Dr. Diehl).

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