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Picture of the Month—Quiz Case
Clarissa Huber, MD;
Antonio Cozzio, MD, PhD;
Christoph Berger, MD;
Lisa Weibel, MD
Arch Pediatr Adolesc Med. 2009;163(11):1061.
A 3-year-old girl presented to our hospital with a 20-month history of a nonhealing crusted lesion on her left cheek. The lesion had suddenly appeared as a red patch with some swelling and occasional oozing. There was no previous trauma. Treatment with topical and systemic antibiotics and topical corticosteroids did not alter the lesion. The family had 2 pet cats, and a travel history revealed a trip to Greece 2 years earlier. On examination there was a solitary erythematous plaque with central crusting and mild swelling measuring 2 x 2 cm on the left cheek but no lymphadenopathy (Figure 1). Bacterial and fungal swab test results were negative and complete blood cell count, C-reactive protein, and renal and liver function test results were normal. A skin biopsy was performed and the histopathologic examination was consistent with a mixed granulomatous inflammation. Periodic acid-Schiff, Brown-Brenn, Ziehl-Neelson, and Giemsa staining as well as tissue cultures for fungi and bacteria, including mycobacteria, were negative. Following appropriate treatment, the lesion resolved completely (Figure 2).
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Figure 1. Solitary nonhealing erythematous plaque with central crust on the left cheek.
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Figure 2. Mild residual telangiectatic erythema 5 months after therapy.
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What is your diagnosis?
Author Affiliations: Department of Dermatology, University Hospital Zurich (Drs Huber, Cozzio, and Weibel); and Division of Infectious Diseases, University Children's Hospital (Dr Berger), Zurich, Switzerland.
SECTION EDITOR: SAMIR S. SHAH, MD
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