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Miriam B. Vos, MD, MSPH; Mary Beth Weber, MPH; Jean Welsh, RN, MPH; Farah Khatoon, MD; Dean P. Jones, PhD; Peter F. Whitington, MD; Craig J. McClain, MD

Arch Pediatr Adolesc Med. 2009;163(7):674-675.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Change in diet is a primary lifestyle modification recommended in the treatment of pediatric nonalcoholic fatty liver disease (NAFLD). However, it is not clear which dietary components are the most important to target. In the United States, the consumption of fructose has increased nearly 50% and, on average, adolescents have a high intake (12% of total daily caloric intake).¹ Diets high in fructose are known to increase plasma lipids and oxidative stress,² both components suspected in NAFLD pathogenesis. Recently, patients with NAFLD were found to consume more fructose compared with matched controls.³ Given this and our previous animal studies,⁴ we designed a pilot study to evaluate a low-fructose diet in children with NAFLD.

Methods

This was a randomized, controlled, 6-month pilot study of . . . [Full Text of this Article]

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