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Picture of the Month—Diagnosis
Arch Pediatr Adolesc Med. 2009;163(4):384.
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Denouement and Discussion: Molluscum Contagiosum
The findings of smooth, waxy umbilicated papules as seen in our case are characteristic of molluscum contagiosum. The patient was also diagnosed with human immunodeficiency virus infection with low CD4+ T-cell counts. A regression of the skin lesions was seen after commencement of highly active antiretroviral therapy.
Molluscum contagiosum is a viral disorder of the skin characterized by discrete, single or multiple, flesh-colored papules. It is caused by Molluscipoxvirus, a large, double-stranded-DNA virus belonging to the same family as cowpox and smallpox.1 There are 4 subtypes, all of which behave clinically identically. Subtype I (75%-90% of cases) is the most common, followed by subtype II.2
Molluscum contagiosum occurs in 2% to 8% of immunocompetent children and in 10% to 20% of human immunodeficiency virus–positive patients; the prevalence in patients with human immunodeficiency virus infection is directly related to the degree of immunocompromise. Since the introduction of highly active antiretroviral . . . [Full Text of this Article]
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Sunita Juliana Ferns and Peter A. Noronha
Arch Pediatr Adolesc Med. 2009;163(4):383.
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