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Attila Szabo, MSc, PhD; Gábor Andrássy, MD, PhD

Arch Pediatr Adolesc Med. 2009;163(1):92-93.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Recently, Kuppermann et al¹ described prolonged QT intervals corrected for heart rate (QTc) during diabetic ketoacidosis (DKA) in 30 children with type 1 diabetes mellitus. These findings contrast with a convincing investigation² published 20 years ago in which, after 24 hours of continuous electrocardiogram (ECG) monitoring, it was concluded that ECG changes were rare and insignificant during the treatment of adults with DKA. In addition, a consensus statement from the American Diabetes Association³ has only connected changes in QT interval during DKA to hypokalemia (widening) and to hyperkalemia (shortening) in children. Clearly, in Kuppermann and colleagues' work, the reported QTc prolongation could not be related to hypokalemia because only 4 of the 14 children with long QTc had hypokalemia. While a connection between QTc prolongation and ketosis could be a plausible explanation, it is also possible that the findings are primarily associated . . . [Full Text of this Article]

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