This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in this journal  Topic Collections  • Pediatrics, Other  • Statistics and Research Methods  • Prognosis/ Outcomes  • Evidence-Based Journal Club  • Drug Therapy  • Adverse Effects  • Drug Therapy, Other  • Emergency Medicine  • Gastroenterology  • Gastrointestinal Diseases  • Alert me on articles by topic  Social Bookmarking   What's this?

Rachel C. Vreeman, MD, MS; S. Maria E. Finnell, MD; Erin R. Cernkovich, PhD; Aaron E. Carroll, MD, MS

Arch Pediatr Adolesc Med. 2008;162(9):866-869.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Acute gastroenteritis (GE) is a common childhood illness.^1-2 Although children with GE frequently have vomiting, current practice recommendations for pediatric GE do not include pharmacologic treatment for vomiting.¹ Furthermore, experimental studies of medications to treat pediatric GE-associated vomiting are limited. In this issue of the Archives, DeCamp et al³ performed a systematic review and meta-analysis to determine if antiemetic treatment reduces vomiting and decreases the need for further intervention in children with GE. Two assessment tools were used to determine the quality rating of each article. The primary outcome measures included cessation of emesis, use of intravenous fluid (IVF) for rehydration, hospital admission, return to care, and medication adverse effects.³

Using computerized databases, references lists, and expert recommendations, DeCamp et al identified 11 prospective controlled studies that met inclusion criteria. . . . [Full Text of this Article]

ARE THE RESULTS OF THIS SYSTEMATIC REVIEW VALID?

Is This a Systematic Review of Randomized Trials?

Does the Systematic Review Describe a Comprehensive and Detailed Search for Relevant Trials?

Were the Individual Studies Assessed for Validity?

Were Individual Patient Data Used in the Analysis?

ARE THE VALID RESULTS OF THIS SYSTEMATIC REVIEW OF THERAPY IMPORTANT?
Are the Results Consistent Across Studies?

What is the Magnitude of the Treatment Effect and How Precise Is It?

CAN WE APPLY THIS VALID, IMPORTANT EVIDENCE ABOUT THERAPY IN CARING FOR OUR PATIENT?
Is Our Patient so Different From Those in the Study That Its Result Cannot Apply?

Is the Treatment Feasible in Our Setting?

What Are Our Patient's Potential Benefits and Harms From the Therapy? Were All Clinically Important Outcomes Considered?

CONCLUSIONS

AUTHOR INFORMATION


CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED ARTICLE

Use of Antiemetic Agents in Acute Gastroenteritis: A Systematic Review and Meta-analysis
Lisa Ross DeCamp, Julie S. Byerley, Nipa Doshi, and Michael J. Steiner
Arch Pediatr Adolesc Med. 2008;162(9):858-865.
ABSTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Dimenhydrinate in Children With Infectious Gastroenteritis: A Prospective, RCT
Uhlig et al.
Pediatrics 2009;124:e622-e632.
ABSTRACT | FULL TEXT  

Reply to letter from Mr Waskett, Professor Morris and Dr Weiss
Van Howe
Int J STD AIDS 2009;20:218-220.
FULL TEXT