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David L. Olds, PhD

Arch Pediatr Adolesc Med. 2008;162(11):1100.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In reply

My point in writing the editorial¹ that accompanied Dr Reynolds' article² was to say that vulnerable children and families will be better served if policies and practices have a stronger foundation in replicated RCTs. Dr Reynolds and his team have made good use of the data that are available to them, but the quasi-experimental nature of this study creates limits that deserve consideration.

I address Dr Reynolds' concerns in order:

1. In neighborhoods characterized by concentrated social disadvantage, there is considerable heterogeneity in parents' psychologic resources, family, and child functioning. This heterogeneity is not explained simply by sociodemographic measures; it is explained by factors like mental health and substance use, aspects of parental functioning not measured in the CPC study. Moreover, better-functioning families are more likely to enroll their children in center-based preschool.^3-4 The authors' decision to limit the analysis to those who completed CPC . . . [Full Text of this Article]

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