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Arch Pediatr Adolesc Med. 2007;161(9):908.

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Denouement and Discussion: Congenital Cutaneous Candidiasis

Histological examination showed a subcorneal pustule filled with neutrophils and a superficial inflammatory infiltrate in the dermis. A direct potassium hydroxide test, as well as a periodic acid–Schiff stain on the biopsy specimen, showed spores and pseudohyphae. Growth of Candida albicans was observed in a Sabouraud culture. Findings of the Gram stain and bacteria culture were negative. Treatment with a topical antifungal (nystatin) was initiated, which caused the skin lesions to disappear in 7 days. After 3 months of follow-up, the patient remained asymptomatic without treatment and the ungual dystrophy resolved.

Mucocutaneous Candida infections are often observed in newborn infants because up to 20% to 25% of pregnant women have vulvovaginitis caused by this yeast.¹ However, few published case reports can be found in the literature on congenital cutaneous candidiasis. It is not known whether such a scarcity of reports reflects underdiagnosis or underreporting of this condition.²

Congenital cutaneous candidiasis . . . [Full Text of this Article]

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Arch Pediatr Adolesc Med. 2007;161(9):907.
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