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Iron Deficiency, Lead Poisoning, and Development
Louis R. Petrone, MD
Arch Pediatr Adolesc Med. 2007;161(5):523.
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Lozoff et al1 demonstrated the persistent negative effects of iron deficiency in infancy on a cohort of children from Costa Rica that the researchers observed through age 19 years. In their recent study, they showed that cognitive scores remained lower in children who were iron deficient in infancy compared with those who were iron sufficient. This finding was more notable in children of lower socioeconomic status, hence the double burden on these children.
Another factor that should be considered in studying this problem is the effect of lead exposure on children's cognitive abilities. The authors point out that iron deficiency correlates with lower socioeconomic status; lead intoxication has a similar association.2 Iron deficiency often coexists with lead intoxication for a variety of reasons related to absorption of the 2 metals from the gastrointestinal tract.3 It has long been known that low-level lead exposure adversely affects test . . . [Full Text of this Article] AUTHOR INFORMATION
RELATED LETTER
Iron Deficiency, Lead Poisoning, and Development—Reply
Betsy Lozoff, Elias Jimenez, and Julia B. Smith
Arch Pediatr Adolesc Med. 2007;161(5):523-524.
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RELATED ARTICLE
Double Burden of Iron Deficiency in Infancy and Low Socioeconomic Status: A Longitudinal Analysis of Cognitive Test Scores to Age 19 Years
Betsy Lozoff, Elias Jimenez, and Julia B. Smith
Arch Pediatr Adolesc Med. 2006;160(11):1108-1113.
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