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Arch Pediatr Adolesc Med. 2006;160:855.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In reply

We thank you for the thoughtful comments. We agree that the long-term consequences of partially hydrolyzed cow's milk formula are not fully known and that the use of PHF for the general population remains controversial. However, the whey-based hydrolysate, which was shown to reduce allergy in high-risk infants, has been approved and used as a routine infant formula in North America for 20 years.

We do not know every potential characteristic or component in formulas (intact protein formulas included) that could be detrimental. It is also clear that not all hydrolysates are compositionally or functionally the same. The formula leading to adverse effects in animals discussed by Professor Marini¹ is a hydrolyzed formula with a median molecular weight of 5000 and made with a combination of casein and whey. This formula is significantly different than either the casein-based extensive hydrolysate or whey-based hydrolysate, which have been studied for . . . [Full Text of this Article]

AUTHOR INFORMATION

Tiffani Hays, MS, RD, LDN; Robert Wood, MD

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