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Arch Pediatr Adolesc Med. 2006;160:854-855.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

We read with particular interest the article by Hays and Wood "A Systematic Review of the Role of Hydrolyzed Infant Formulas in Allergy Prevention"¹ and appreciate being quoted twice. We confirm our preference for the use of partially hydrolyzed formula (PHF) for the nutritional prevention of allergy, but only in highly atopic subjects. Extensively hydrolyzed formulas are more expensive, have a bad taste, and do not satisfy the nutritional needs of the growing baby.²

Changes in intestinal microflora³ should be taken into account because of their influence on the future development of allergies, which is similar to that observed in breastfed babies; peptides have a bifidogenic effect. Adding prebiotics to infant formula has a permanent bifidogenic effect as it increases lactobacilli and markedly decreases previously present pathogen germs.⁴ However, to obtain a clear advantage, any intervention must be part of a more general nutritional program and environmental advice.

We do . . . [Full Text of this Article]

AUTHOR INFORMATION

Antonio Marini, MD; Massimo Agosti, MD; Carla Colombo, MD

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