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Laboratory Testing for Drug Abuse
Arch Pediatr Adolesc Med. 2006;160:854.
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The Levy et al article1 on adolescent physicians' knowledge of the practices of screening for drug abuse is timely. We have long felt that practicing physicians' knowledge of drug testing has not recognized the technical and ethical issues involved.2 In our experience, clinical testing for drug abuse does not follow the policies and procedures outlined for federal workplace testing. In fact, most hospital laboratories do not have established policies for validation of specimens and many do not have the ability to perform confirmatory testing, which in federal testing requires gas chromatography/mass spectroscopy. We disagree with the blanket statement of Levy et al that urine drug screenings do not detect oxycodone and ecstasy (3,4-methylenedioxymethamphetamine). The ability to detect these substances depends on the cross-reactivity of the particular immunoassay used. The technology for immunoassays is continually evolving and many of the currently used assays do, in fact, detect these substances. Physicians who . . . [Full Text of this Article]AUTHOR INFORMATION
Elizabeth A. Warner, MD;
Peter D. Friedmann, MD
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Laboratory Testing for Drug Abuse—Reply
Sharon Levy, Sion Kim Harris, Lon Sherritt, Michelle Angulo, and John R. Knight
Arch Pediatr Adolesc Med. 2006;160(8):854.
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Drug Testing of Adolescents in Ambulatory Medicine: Physician Practices and Knowledge
Sharon Levy, Sion Kim Harris, Lon Sherritt, Michelle Angulo, and John R. Knight
Arch Pediatr Adolesc Med. 2006;160(2):146-150.
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