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Implications for Primary Care of Diabetes and Impaired Fasting Glucose Prevalence in Adolescents
Arch Pediatr Adolesc Med. 2006;160:550-552.
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In his article in this issue, Duncan1 estimates the prevalence for type 1 diabetes mellitus (T1DM) and type 2 diabetes mellitus (T2DM) from self-reports by 4370 adolescents aged 12 to 19 years in the National Health and Nutrition Examination Survey, and frequency of impaired fasting glucose in a tested subsample of subjects. A fundamental problem in interpreting the diabetes prevalence data is the case definition of T1DM and of T2DM. During the past several decades, we have gone from classifying the main forms of diabetes by age group (juvenile onset vs maturity onset) to differentiating by treatment (insulin-dependent vs noninsulin-dependent) to the contemporary separation by etiology.2 Type 1 diabetes mellitus is a disease predominantly of autoimmune-mediated insulin deficiency, whereas T2DM results from a combination of insulin resistance and inadequate islet cell capacity to meet the increased insulin demands. The case definition in this study, which lacks validation from medical records, . . . [Full Text of this Article]AUTHOR INFORMATION
Arlan L. Rosenbloom, MD
RELATED ARTICLE
Prevalence of Diabetes and Impaired Fasting Glucose Levels Among US Adolescents: National Health and Nutrition Examination Survey, 1999-2002
Glen E. Duncan
Arch Pediatr Adolesc Med. 2006;160(5):523-528.
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