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Does the Use of Oxycodone Affect Diagnostic Accuracy in Children With Acute Abdominal Pain?
Arch Pediatr Adolesc Med. 2005;159:326-328.
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Historically, opioid analgesia has been thought to mask symptoms, alter physical exam findings, delay diagnosis, and increase morbidity and mortality for patients with acute abdominal pain of unclear etiology.1 However, studies in children and adults have demonstrated that administering intravenous opioids to patients with acute abdominal pain does not delay diagnosis or adversely affect diagnostic accuracy.1-2 In this issue of ARCHIVES, Kokki et al3 present a randomized, double-blind, placebo-controlled clinical trial examining the consequences of buccal delivery of oxycodone on pain relief and diagnostic accuracy in children evaluated in the emergency department (ED) with moderate to severe acute abdominal pain. Using the Users’ Guide to the Medical Literature,4-5 we reviewed this study with regard to the validity of results, size and precision of the treatment effect, and generalizability and applicability of outcomes.
ARE THE RESULTS IN THIS ARTICLE VALID?
Was the Study Randomized? Yes, but more details about randomization would allow the reader to determine . . . [Full Text of this Article] WHAT ARE THE RESULTS? WILL THE RESULTS HELP ME IN CARING FOR MY PATIENTS? CONCLUSIONS
AUTHOR INFORMATION
Michael E. Bowen, BA;
Katherine A. Poehling, MD, MPH;
Veronica L. Gunn, MD, MPH;
Kecia N. Carroll, MD, MPH;
S. Todd Callahan, MD, MPH;
Patrick G. Arbogast, PhD;
William O. Cooper, MD, MPH
RELATED ARTICLE
Oxycodone vs Placebo in Children With Undifferentiated Abdominal Pain: A Randomized, Double-blind Clinical Trial of the Effect of Analgesia on Diagnostic Accuracy
Hannu Kokki, Hannu Lintula, Kari Vanamo, Marjut Heiskanen, and Matti Eskelinen
Arch Pediatr Adolesc Med. 2005;159(4):320-325.
ABSTRACT
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