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Reevaluating Antibiotic Therapy for Urinary Tract Infections in Children
Arch Pediatr Adolesc Med. 2005;159:992-993.
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Urinary tract infection (UTI) is a common pediatric problem, with 2% of all children experiencing one by the age of 10 years. In addition, between 2.5% and 10% of children with fever without localizing signs have a UTI.1 Thus, the pediatrician is faced with treatment decisions frequently. For many years, therapy was straightforward, but the situation has changed. Both the lay and medical literature report that bacteria are becoming increasingly resistant to commonly used antibiotics. Gram-negative enteric organisms, the most common cause of UTI, are particularly problematic. With widespread use of expanded spectrum antibiotics, a number of highly effective resistance mechanisms have evolved.2 Clinicians are often uncertain how to treat.
When treating the first UTI in a child, it is generally assumed that Escherichia coli is the culprit because it is isolated in 80% to 90% of such patients. Currently, E coli isolates are resistant to ampicillin in nearly 50% . . . [Full Text of this Article] AUTHOR INFORMATION
Aida Yared, MD;
Kathryn M. Edwards, MD
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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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