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Arch Pediatr Adolesc Med. 2004;158:207-208.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Functionally disabling chronic fatigue is a familiar complaint in adult primary care settings, infrequent among adolescents, and very rare in children. For more than a century, a syndrome of chronic fatigue associated with various physical and cognitive symptoms has been described with terms including neurasthenia, Akureyri disease, Royal Free disease, myalgic encephalomyelitis, postviral syndrome, and chronic fatigue syndrome (CFS). Scant data estimate that pediatric CFS has a prevalence ranging from 23 to 116 of 100 000 children and adolescents with an approximate 2.5:1 female to male ratio.¹ Various diagnostic criteria have been proposed, but most researchers today use the 1994 Centers for Disease Control and Prevention (Atlanta, Ga) revised CFS criteria² that require the presence of medically unexplained, profound, persistent or intermittent fatigue associated with significant functional disability for greater than 6 months and the presence of 4 additional symptoms (eg, headache, polyarthralgia, tender adenopathy, impaired . . . [Full Text of this Article]

Mark Scott Smith, MD
Adolescent Medicine Section
Children's Hospital and Regional Medical Center
Mailstop 4H-1
Box 359300
Seattle, WA 98105

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