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Finding the Yellow Brick Road

Arch Pediatr Adolesc Med. 2004;158:111-112.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In this issue of the ARCHIVES, the 2 studies by Bordley et al¹ and King et al² clearly point out the conundrums, confusion, and concerns regarding the currently available methods of diagnosis and testing as well as pharmacologic therapies for bronchiolitis in young children. These well-designed reviews conclude that the present indications for testing and efficacy of the therapeutic modalities discussed are insufficient. The results produce 2 major questions: Why is no benefit or efficacy demonstrated, and where do we go from here?

The lack of effective approaches to management may result partly from differences in design and outcome measures in the various studies. Perhaps more important, the populations being studied are not uniform (clinically, demographically, environmentally, or genetically). For instance, corticosteroids do not appear to benefit children who are first-time wheezers but may be indicated in those with recurrent wheezing.³ Children from families with a history of atopy may . . . [Full Text of this Article]

Caroline Breese Hall, MD
Departments of Pediatrics and Medicine, Infectious Diseases, Box 689
University of Rochester School of Medicine and Dentistry
601 Elmwood Ave
Rochester, NY 14642
(e-mail: Caroline_Hall@urmc.rochester.edu)

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