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Sex Differences in Morbidity and Mortality Among Children With Perinatally Acquired Human Immunodeficiency Virus Infection in New York City
Arch Pediatr Adolesc Med. 2004;158:1187-1188.
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Studies on sex differences among adults with human immunodeficiency virus (HIV) have shown conflicting results. We sought to evaluate sex differences in morbidity and mortality among perinatally HIV-infected children. The study population included HIV-infected children born in 1990-1998 and enrolled in the Centers for Disease Control and Prevention (Atlanta, Ga)–funded the Pediatric Spectrum of HIV Disease project in 10 hospitals in New York City, NY. Medical records were reviewed every 6 months or until the child was no longer in care at the sites or died. All study children, stratified into 3 birth cohorts (1990-1992, 1993-1995, and 1996-1998), were evaluated for HIV infection within 3 months of birth.
This study includes 269 boys and 303 girls. During follow-up, 58 boys and 70 girls died; 117 boys and 111 girls developed AIDS-defining conditions. Tests for sex differences in Kaplan-Meier curves for survival and AIDS incidence were not significant overall and within . . . [Full Text of this Article] AUTHOR INFORMATION
Kai-Lih Liu, PhD, MPH;
Vicki Peters, MD;
Jeremy Weedon, PhD;
Pauline Thomas, MD;
Kenneth Dominguez, MD, MPH
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