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Arch Pediatr Adolesc Med. 2004;158:1017.

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In reply

We thank Dr Harkavy for his careful reading of our article. First, we appreciate the difficulty in the use of the word control to describe the reference group in any epidemiologic study. Dr Harkavy refers to a control group as in a randomized trial where there is an intervention; however, as seen in the use of the word control in case-control studies, a control group can also refer to any population of patients to whom the study is comparing the group of interest.¹ In our study, we chose to focus on the population of infants with macrocephaly who were examined at a pediatrician’s office or in a neonatal follow-up group. Our "cases" were those infants with the conditions of interest (ie, benign extra-axial fluid). Thus, our "controls" were those infants without extra-axial fluid. We realize that to answer other questions a different cohort of patients should be recruited. . . . [Full Text of this Article]

AUTHOR INFORMATION

Scott A. Lorch, MD, MSCE; Judy Bernbaum, MD

RELATED ARTICLE

Outcomes After "Benign" Extra-Axial Fluid
Kenneth Harkavy
Arch Pediatr Adolesc Med. 2004;158(10):1017.
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