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Fever, Hepatosplenomegaly, and Pancytopenia in a 5-Month-Old Infant
Jason M. Kane, MD;
Kara Schmidt, MD;
James H. Conway, MD
Arch Pediatr Adolesc Med. 2003;157:201-205.
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Hepatosplenomegaly in a young child can be an ominous physical finding, potentially representing a metabolic, malignant, or infectious process. We present the case of a 5-month-old girl who had fever, hepatosplenomegaly, and hematologic abnormalities at the initial examination. This case demonstrates how a comprehensive understanding of the pathophysiologic characteristics of hepatosplenomegaly and a systematic and thorough workup can help ensure that important diagnoses are not overlooked.
Clinical Presentation (Kara Schmidt, MD): A previously healthy 5-month-old girl presented to James Whitcomb Riley Hospital for Children, Indianapolis, Ind, with a 1-week history of fever (temperature to 39.5°C), diarrhea, and irritability. The family denied that the infant had exhibited any respiratory symptoms or rash and reported only 1 episode of emesis. She had been evaluated at a local emergency department 4 days before presentation. The results of a chest radiograph and a . . . [Full Text of this Article] COMMENT
From the Department of Pediatrics, Section of Pediatric Infectious Diseases, Indiana University School of Medicine, Indianapolis.
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Instructions for Authors
Arch Pediatr Adolesc Med 2005;159:197-197.
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Arch Pediatr Adolesc Med 2004;158:709-709.
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Arch Pediatr Adolesc Med 2004;158:92-92.
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Arch Pediatr Adolesc Med 2003;157:832-832.
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