 |
|
Review of a Randomized Trial Comparing 2 Cerumenolytic Agents
Arch Pediatr Adolesc Med. 2003;157:1181-1183.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
THE STUDY we review by Whatley et al1 is a randomized, double-blind, controlled interventional trial comparing the relative effectiveness of 2 agents—docusate sodium (Colace), triethanolamine polypeptide (Cerumenex), and saline control—in the removal of cerumen obstructing visualization of the tympanic membrane. The investigators' objective was to determine whether a significant difference existed between these 2 agents with or without irrigation in removing cerumen obstruction.1 The authors used a convenience sample of 93 pediatric patients with cerumen occlusion of the external auditory canal. The subjects were aged 6 months through 5 years and were brought to 1 of 2 sites for treatment: a children's hospital emergency department or a large general pediatric clinic. Patients were eligible if they had complete or partial cerumen obstruction on the basis of clinical examination by 1 of 4 investigators. After subject randomization, a study nurse instilled 1 mL of 1 of the treatment agents or . . . [Full Text of this Article]FRAMING THE QUESTION
SAMPLING AND RANDOMIZATION
ASSESSMENT
INTERPRETATION OF RESULTS
CONCLUSIONS
Henry M. Lemon, MD;
Jennifer Mazyck-Brown, PharmD;
Tara A. Cancellaro, MD;
Paul M. Darden, MD;
William T. Basco, Jr, MD
Charleston, SC
RELATED ARTICLE
Randomized Clinical Trial of Docusate, Triethanolamine Polypeptide, and Irrigation in Cerumen Removal in Children
Valerie N. Whatley, Carey L. Dodds, and Ronald I. Paul
Arch Pediatr Adolesc Med. 2003;157(12):1177-1180.
ABSTRACT
| FULL TEXT
|
