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Odorants in Breast Milk
Arch Pediatr Adolesc Med. 2003;157:1031.
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Infants can distinguish the odor of their mother's breast milk from that of other mothers.1 However, infants prefer the odor of other mothers' breast milk to that of formula,2 implying that the pattern of odor compounds liberated from formula differs from that of human milk. To identify odorant compounds of breast milk vs formula, we performed gas chromatography/olfactometry (GC/O) on premature infant formula (Similac Special Care 24 cal/oz; Ross Products, Division of Abbott Laboratories, Columbus, Ohio) and on breast milk from mothers of premature infants. This population was chosen because of our interest in the therapeutic effects of controlled odor exposure on feeding in this population.3
Subjects pumped breast milk using a manual expression technique. Specimens were aliquotted into 30-mL glass vials and frozen within 15 minutes. Chemical identification of odorants4 was based on an exact match of odor character and retention index on GC/O with that of an authentic . . . [Full Text of this Article]
Peter M. Bingham, MD
Fletcher Allen Health Care/University of Vermont One S Prospect St Burlington, VT 05401 (e-mail: peter.bingham@vtmednet.org) Debbie Stevens-Tuttle, BS Burlington
Edward Lavin, BS;
Terri Acree, PhD
Geneva, NY
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