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The Evaluation of Young Febrile Children for Occult Bacteremia
Time to Reevaluate Our Approach?
Arch Pediatr Adolesc Med. 2002;156:855-857.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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THE EVALUATION of young nontoxic-appearing febrile children has
stirred up considerable debate, with much of the controversy surrounding the
identification of occult bacterial illness, specifically bacteremia. Despite
the publication of guidelines to assist clinicians with decision making regarding
the evaluation of febrile infants and young children,1-2
wide variations persist in both the evaluation and treatment of these children.3-4
In the decade following the introduction of a conjugate vaccine against Haemophilus influenzae type b, but prior to the licensure
of the conjugate pneumococcal vaccine, the prevalence of occult bacteremia
in nontoxic-appearing children between 3 and 36 months of age with
temperatures higher than 39°C declined to roughly 2%.5-7
More than 90% of episodes of occult bacteremia were due to Streptococcus pneumoniae. Of children with occult S pneumoniae bacteremia, approximately 3% to 5% go on to develop pneumococcal
meningitis if not treated with empirical antibiotics.8-9
Thus, pneumococcal meningitis develops in only . . . [Full Text of this Article]
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