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Is Primary Prevention of Allergy-Mediated Asthma a Viable Idea?
Arch Pediatr Adolesc Med. 2002;156:967-968.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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IN THIS issue of the ARCHIVES, Dr Tsitoura and her colleagues1 report on a remarkable international dataset of infants
and young children at high risk for becoming allergic to, but not yet sensitized
to, house dust mites. In a primary prevention trial, these children were randomized
either to an intervention group that received a simple house dust mitereduction
strategy (mattress encasement and detailed preventive environmental recommendations,
such as hot-washing of sheets and bedding) or to a control group, whose parents
received information about general indoor environmental issues. After 1 year,
children in the intervention group were less than half as likely as controls
to have developed allergy to house dust mites (3.0% vs 6.5%). Furthermore,
the frequency of asthma symptoms and asthma diagnoses was greater among the
children who became sensitized to house dust mites during the study year.
How potentially significant are these findings in the context of allergies
. . . [Full Text of this Article]
RELATED ARTICLE
Randomized Trial to Prevent Sensitization to Mite Allergens in Toddlers and Preschoolers by Allergen Reduction and Education: One-Year Results
Stella Tsitoura, Katerina Nestoridou, Panayotis Botis, Wilfried Karmaus, Calin Botezan, Jurgis Bojarskas, Hassan Arshad, Joachim Kuehr, Johannes Forster, and for the SPACE Group
Arch Pediatr Adolesc Med. 2002;156(10):1021-1027.
ABSTRACT
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