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Hormone-Containing Hair Product Use in Prepubertal Children
Arch Pediatr Adolesc Med. 2002;156:85-86.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Some cosmetics contain estrogens, representing a potential source of
exogenous estrogen for children. In contrast to pharmaceutical preparations,
the Food and Drug Administration (Rockville, Md) does not regulate cosmetics
containing less than 10 000 IU of estrogen per ounce, only stating that
the label should direct consumers to limit the amount of product used to less
than 20 000 IU/mo.1-2
A therapeutic dose of oral ethinyl estradiol for hormone-replacement therapy
in adults is 0.02 to 0.05 mg/d (4000-10 000 IU/d). An equivalent therapeutic
transdermal estradiol dose for hormone-replacement therapy is 0.05 mg/d.
Two case series suggest that exogenous hormones found in hair products
may be associated with early pubertal development in African American girls.2-3 In 3 of 4 cases, pubertal characteristics
regressed on discontinuation of these products.3
Patterns of use of hormone-containing hair products (HCHPs) are unknown. One
survey of parents at 4 southern US Army hospital clinics revealed that 64%
of African . . . [Full Text of this Article]
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