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Dianne S. Elfenbein, MD; Patricia J. Emmanuel, MD
From the Department of Pediatrics, University of South Florida, Tampa.

Arch Pediatr Adolesc Med. 2001;155:849-850.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

AN 8-YEAR-OLD BOY with human immunodeficiency virus (HIV) was seen for routine evaluation. At the time of HIV diagnosis (age 4 years), his CD4 cell count was 17 cells/µL (reference range, >1000 cells/µL), and findings from neurologic examination were normal. Treatment was started with zidovudine, trimethoprim sulfate, rifabutin, and monthly intravenous immunoglobulin, but the CD4 cell count remained low. At age 6 years, he had been performing poorly in school. Findings from neurologic examination showed 2 to 3 beats of ankle clonus bilaterally. A magnetic resonance imaging study (MRI) had been obtained. The patient later developed anemia, leukopenia, elevated creatine phosphokinase levels, and elevated lactic dehydrogenase levels, all of which resolved when zidovudine was discontinued. At age 7 years, he was hospitalized for persistent fever with no source found. Nephrotic syndrome was diagnosed based on renal biopsy findings showing minimal changes of . . . [Full Text of this Article]