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Human Monocytic Ehrlichiosis: A Potentially Severe Disease in Children
Arch Pediatr Adolesc Med. 2000;154:847-849.
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The spectrum of diseases caused by human monocytic ehrlichiosis (HME) in children ranges from asymptomatic to severe and even fatal.1-5 The infection often goes unrecognized1, 6 because it may be very mild and not lead the family to seek medical attention, or because the physician may not be familiar with it. The importance of diagnosing HME in children is that appropriate early antibiotic therapy with a tetracycline leads to rapid defervescence and recovery.2, 6-7 Moreover, when untreated, HME may be fatal. We report 2 cases of severe HME in children that required intensive care management.
Report of a Case
Case 1
A 6-year-old white girl with hypotension, fever, lethargy, and pancytopenia was transferred to the pediatric intensive care unit at the Johns Hopkins Medical Institutions (Baltimore, Md) from another hospital. She had a 10-day history of fever (temperature to 40°C), headache, prominent hyperosmia, photophobia, tender posterior cervical lymphadenopathy, and 2 episodes of emesis. She was receiving prophylactic trimethoprim-sulfamethoxazole, . . . [Full Text of this Article] Case 2 Comment
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Human Monocytic Ehrlichiosis
Stone et al.
JAMA 2004;292:2263-2270.
ABSTRACT
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