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Pathological Case of the Month
Shohreh Iravani, MD;
Diane Debich-Spicer, BS;
Enid Gilbert-Barness, MD
From the Department of Pathology, University of South Florida, Tampa (Dr Iravani and Ms Debich-Spicer), and the Department of Pathology, Tampa General Hospital, University of South Florida, Davis Island (Dr Gilbert-Barness).
Arch Pediatr Adolesc Med. 2000;154:747-748.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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A GRAVIDA 2, para 1 mother at 23 weeks' gestation delivered vaginally on termination of pregnancy a 520 g stillborn female fetus (Figure 1) with multiple skeletal and central nervous system anomalies. The pregnancy was uncomplicated without signs or symptoms of infection. The mother denied tobacco, alcohol, or other drug use. Postmortem radiographic studies (Figure 2) disclosed short lower extremities with anterior bowing of the femurs, tibias, and fibulas as well as 11 paired thin ribs. At autopsy, there was talipes equinovarus, dolichocephaly, and malformed olfactory bulbs. External female genitalia were noted, and cytogenetics revealed a normal 46,XX karyotype. The long bones of the lower extremities were angulated (Figure 3). Findings from the cardiovascular, respiratory, and genitourinary systems were unremarkable. A second trimester placenta with trivascular umbilical cord showed no significant abnormality.
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Figure 1.
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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Campomelic Dysplasia
Eger
Journal of Diagnostic Medical Sonography 2005;21:343-349.
ABSTRACT
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