 |
|
Making History
Thomas Francis, Jr, MD, and the 1954 Salk Poliomyelitis Vaccine Field Trial
Sarah Marie Lambert, BA;
Howard Markel, MD, PhD
Arch Pediatr Adolesc Med. 2000;154:512-517.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
This article focuses on the poliomyelitis vaccine field trial directed by Thomas Francis, Jr, MD, of the University of Michigan Vaccine Evaluation Center and sponsored by the National Foundation for Infantile Paralysis (NFIP) or, as it was better known to the public, the March of Dimes. It was a landmark in the widescale testing of a vaccine and the ethical use of human subjects. Millions of American parents readily volunteered their healthy children to participate. A total of 150,000 volunteers, including schoolteachers, physicians, nurses, and health officers all endorsed the study and donated their time and effort to make it successful.1(p269) Avoiding the use of marginalized groups, the field trial purposefully did not involve institutionalized children; instead, it was based in 15,000 public schools in 44 of the 48 states as clinic sites.1(268) A group of 650,000 children received some . . . [Full Text of this Article]
From the Department of Pediatrics and Communicable Diseases, Historical Center for the Health Sciences, University of Michigan Medical School, Ann Arbor. Ms Lambert is now a medical student at Columbia University College of Physicians and Surgeons, New York, NY.
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
The History Of Vaccines And Immunization: Familiar Patterns, New Challenges
Stern and Markel
Health Aff (Millwood) 2005;24:611-621.
ABSTRACT
| FULL TEXT
Evidence-Based Public Health: Moving Beyond Randomized Trials
Victora et al.
Am. J. Public Health 2004;94:400-405.
ABSTRACT
| FULL TEXT
|
