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Arch Pediatr Adolesc Med. 1999;153:1202-1203.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In their recent report, Hamrick and Fordham¹ provided reassurance that neonatal ovarian cyst (OC) can be managed in pediatric practice. They nicely illustrated the diagnosis and treatment of a patient with OC, which was detected because of an abdominal mass and associated clinical symptoms. In addition to familiar clinical issues related to neonatal OC, mainly aspects of surgical management, we would like to add here another clinical aspect of the management of OC, that of endocrinology.

During the past few years we encountered 5 patients with OC who were given the diagnosis prenatally, which allowed us to measure their circulating levels of estradiol (E₂) serially after birth. Two of the 5 patients who had unilateral large cysts (5 cm in diameter) underwent periodic ultrasound-guided percutaneous cyst aspiration for prevention of ovarian torsion until 1 month of age; the E₂ level of the cystic fluid was 9200 pmol/L and 25,100 . . . [Full Text of this Article]