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  Vol. 152 No. 9, September 1998 TABLE OF CONTENTS
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Facial Palsy in Lyme Disease

Arch Pediatr Adolesc Med. 1998;152:928-929.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Belman et al1 do not report whether the accepted confirmatory serologic test for Lyme disease, the serum immunoblot,2 was performed on their patients. It is well established that enzyme-linked immunosorbent assay (ELISA) methods for total antibodies to Borrelia burgdorferi have a high false-positive rate. No cerebrospinal fluid assay, other than culture for B burgdorferi or polymerase chain reaction (PCR) for B burgdorferi DNA, is accepted as specific. Thus, Lyme disease was not confirmed in their patients and several or all may have had idiopathic Bell palsy.

The diagnosis of recent or current B burgdorferi infection in a patient with acute facial palsy can be made by performing serum IgM immunoblotting during the acute phase (<=4 weeks after the onset of infection), which helps in making the decision to initiate early antibiotic treatment.3 Demonstration of seroconversion by IgG immunoblot in the convalescent period is confirmatory.

Sunil K. Sood, MD
Pediatric . . . [Full Text of this Article]



THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Practice Parameter: Treatment of nervous system Lyme disease (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology
Halperin et al.
Neurology 2007;69:91-102.
ABSTRACT | FULL TEXT  





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