
Aluminum Toxicity
Arch Pediatr Adolesc Med. 1998;152:511-512.
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Recently attention has been drawn to aluminum toxicity in infants. Bishop et al1 have reported aluminum toxicity as a complication of hyperalimentation in preterm infants. Encephalopathy in children has occurred secondary to aluminum toxicity from dialysis.2 Increased concentrations of aluminum in the brain of a parenterally fed premature infant have been demonstrated3 and high tissue aluminum concentrations after death have been reported.4-5 Aluminum neurotoxicity has been reported in neonates with uremia who were fed a cow's milkbased formula.6 Heparin and colloids can also be contaminated with aluminum.7-8
Patient Report
We observed a 9-year-old girl who had been noted to not be progressing developmentally at age 2 months. Her condition was diagnosed at age 4 months as a neurodegenerative disorder with profound mental retardation, multifocal seizures, spastic tetraplegia, growth retardation, and spasticity. Diagnoses of Leigh encephalopathy as well as multiple other metabolic diseases were considered; however, all enzyme levels related to these disorders . . . [Full Text of this Article] Comment
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Aluminum Exposure From Pediatric Parenteral Nutrition: Meeting the New FDA Regulation
Poole et al.
JPEN J Parenter Enteral Nutr 2008;32:242-246.
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