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  Vol. 152 No. 4, April 1998 TABLE OF CONTENTS
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Picture of the Month

Naji A. Kulaylat, MD; Hassib H. Narchi, MD; Samih A. Baalbaki, MD; Walter W. Tunnessen, Jr, MD
From the Saudi Aramco-Al-Hasa Health Center, Saudi Aramco Medical Services Organization, Mubarraz, Saudi Arabia (Drs Kulaylat, Narchi, and Baalbaki); and The American Board of Pediatrics, Chapel Hill, NC (Dr Tunnessen).

Arch Pediatr Adolesc Med. 1998;152:405-406.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

A 13-YEAR-OLD boy, the offspring of first cousins, presented with long-standing, brown-black, hyperpigmented, velvety, hyperkeratotic plaques over both ankles, axillae, neck, and groin (Figure 1). His face was acromegaloid and he had a generalized paucity of subcutaneous fat (Figure 2). His muscles were prominent and his abdomen distended (Figure 3). In addition, he was hirsute and his genitalia were enlarged. A paternal uncle has had similar skin lesions since he was a child.


Figure 1.


Figure 2.


Figure 3.


Denouement and Discussion: Generalized Lipodystrophy

Figure 1. The axilla appears hyperpigmented and velvety, characteristic of acanthosis nigricans.

Figure 2. The face is acromegaloid and the neck shows changes of acanthosis nigricans.

Figure 3. The muscles are prominent and the abdomen is distended secondary to hepatomegaly.

Generalized lipodystrophy, also known as . . . [Full Text of this Article]







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