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  Vol. 152 No. 12, December 1998 TABLE OF CONTENTS
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Rickets and Secondary Craniosynostosis Associated With Long-term Antacid Use in an Infant

Arch Pediatr Adolesc Med. 1998;152:1243-1245.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Oral antacids are occasionally prescribed for infantile colic, gastroesophageal reflux, esophagitis, and other peptic disorders.1 It has long been known that prolonged treatment with nonabsorbable antacids such as aluminum-magnesium hydroxides can limit gastrointestinal absorption of phosphorus.2 Hypophosphatemic bone disease, either rickets or osteomalacia, is a well-known complication of impaired renal tubular resorption of phosphate,3 but is rarely caused by nutritional phosphate deprivation. Although antacid-induced hypophosphatemic osteomalacia has been extensively reported in adults,4-9 very few reports exist in the pediatric literature.10-11 We report a case of rickets and secondary craniosynostosis in an infant following long-term administration of an aluminum-containing antacid.

Patient Report.

A 10-month-old white male infant was referred for evaluation of a bulging anterior fontanelle and growth failure. He was born at 37 weeks' gestation by cesarean section to a 29-year-old gravida 2, para 1 mother. Weight, length, and head circumference at birth were at the 75th, 25th, and 50th percentiles for . . . [Full Text of this Article]


Comment.

RELATED ARTICLE

A New Form of Rickets During Infancy: Phosphate Depletion–Induced Osteopenia Due to Antacid Ingestion
Russell W. Chesney
Arch Pediatr Adolesc Med. 1998;152(12):1168-1169.
EXTRACT | FULL TEXT  


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Calcium and Phosphorous in Pediatric Parenteral Nutrition
Marks and Crill
Journal of Pharmacy Practice 2004;17:432-446.
ABSTRACT  

Antacid-Induced Rickets in Infancy
Pattaragarn and Alon
CLIN PEDIATR 2001;40:389-393.
ABSTRACT  

A New Form of Rickets During Infancy: Phosphate Depletion-Induced Osteopenia Due to Antacid Ingestion
Chesney
Arch Pediatr Adolesc Med 1998;152:1168-1169.
FULL TEXT  





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