This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on ISI (1)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Topic Collections  • Men's Health  • Men's Health, Other  • Adolescent Medicine  • Pediatrics, Other  • Quality of Life  • Endocrine Diseases  • Diabetes Mellitus  • Alert me on articles by topic  Social Bookmarking   What's this?

SEARCH for Diabetes in Youth Study

Michelle J. Naughton, PhD, MPH; Andrea M. Ruggiero, MS; Jean M. Lawrence, ScD, MPH, MSSA; Giuseppina Imperatore, MD, PhD; Georgeanna J. Klingensmith, MD; Beth Waitzfelder, PhD; Robert E. McKeown, PhD; Debra A. Standiford, RN, MSN, CNP; Angela D. Liese, PhD, MPH; Beth Loots, MPH, MSW; for the SEARCH for Diabetes in Youth Study Group

Arch Pediatr Adolesc Med. 2008;162(7):649-657.

Objective  To examine the associations between demographic and diabetes management variables and the health-related quality of life (HRQOL) of youths with type 1 or type 2 diabetes mellitus (DM).

Design  Cross-sectional study.

Settings  Selected populations in Ohio, Washington, South Carolina, Colorado, Hawaii, and California; health service beneficiaries in 3 American Indian populations; and participants in the Pima Indian Study in Arizona.

Participants  Two thousand four hundred forty-five participants aged 8 to 22 years in the SEARCH for Diabetes in Youth Study.

Main Outcome Measure  Pediatric Quality of Life Inventory scores.

Results  Among youths with type 2 DM, HRQOL was lower compared with those with type 1. Among those with type 1 DM, worse HRQOL was associated with a primary insurance source of Medicaid or another government-funded insurance, use of insulin injections vs an insulin pump, a hemoglobin A_1c value of at least 9%, and more comorbidities and diabetes complications. There was a significant age x sex interaction, such that, in older groups, HRQOL was lower for girls but higher for boys. For youths with type 2 DM, injecting insulin at least 3 times a day compared with using an oral or no diabetes medication was associated with better HRQOL, and having 2 or more emergency department visits in the past 6 months was associated with worse HRQOL.

Conclusions  Youths with types 1 and 2 DM reported HRQOL differences by type of treatment and complications. The significant age x sex interaction suggests that interventions to improve HRQOL should consider gender differences in diabetes adjustment and management in different age groups.

Author Affiliations: Departments of Social Sciences and Health Policy (Dr Naughton) and Biostatistical Sciences (Ms Ruggiero), Division of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina; Research and Development, Kaiser Permanente Southern California, Pasadena (Dr Lawrence); Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, Georgia (Dr Imperatore); Barbara Davis Center, University of Colorado School of Medicine, Denver (Dr Klingensmith); Pacific Health Research Institute, Honolulu, Hawaii (Dr Waitzfelder); Department of Epidemiology and Biostatistics, University of South Carolina, Columbia (Drs McKeown and Liese); Division of Endocrinology, Children's Hospital Medical Center, Cincinnati, Ohio (Ms Standiford); and Endocrinology, Children's Hospital and Regional Medical Center, Seattle, Washington (Ms Loots).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Generic and Diabetes-specific Parent-Child Behaviors and Quality of Life Among Youth with Type 1 Diabetes
Weissberg-Benchell et al.
J Pediatr Psychol 2009;0:jsp003v1-jsp003.
ABSTRACT | FULL TEXT