 |
|
Subsequent Sexually Transmitted Infection in Urban Adolescents and Young Adults
Donald P. Orr, MD;
Krystal Johnston, MD;
Edward Brizendine, MS;
Barry Katz, MD;
J. Dennis Fortenberry, MD, MS
Arch Pediatr Adolesc Med. 2001;155:947-953.
Objective To compare the rates of subsequent infection with Chlamydia trachomatis, Neisseria gonorrhoeae,
or Trichomonas vaginalis in a group of high-risk
adolescents and young adults.
Methods At the time of treatment, 444 unmarried teenagers and young adults aged
13 to 25 years were enrolled from an urban sexually transmitted disease clinic
and 3 community-based primary care clinics. Subjects were infected with C trachomatis, N gonorrhoeae,
or T vaginalis, were diagnosed as having nongonococcal
urethritis (in men), or were uninfected sexual contacts with one of these
infections. Subjects returned at 1, 3, 5, and 7 months.
Results The rate of subsequent infection was substantial. Forty percent of men
and 53% of women who were uninfected contacts at enrollment were estimated
to be infected within 7 months; 60% of men and 73% of women infected at enrollment
were estimated to be reinfected. Among women, subjects who were infected at
enrollment had a shorter time to subsequent infection (median, 140 days) compared
with uninfected contacts (median, 209 days) (P =
.04). Among men, findings were similar, but the difference in median time
to subsequent infection was not significant (P =
.08). Baseline characteristics that predicted shorter time to reinfection
were female sex and infection at enrollment. When sexual behaviors in the
2 months preceding each subsequent data collection visit were included in
the model, only being female and reporting at least one new interval sexual
partner were significant predictors of subsequent sexually transmitted infections.
Conclusions These data support recent research that has found high rates of subsequent
infection among high-risk adolescents and young adults. Contacts of a sexually
transmitted infection appear to be at equally high risk for subsequent infection
as those with a personal history of infection. Our data suggest that more
frequent than annual screening for N gonorrhoeae, C trachomatis, and T vaginalis
would be appropriate in at-risk adolescent and young adult populations, including
individuals who are uninfected sexual contacts to a sexually transmitted infection.
From the Section of Adolescent Medicine, Department of Pediatrics (Drs
Orr, Johnston, and Fortenberry), and Division of Biostatistics, Department
of Medicine (Mr Brizendine and Dr Katz), Indiana University School of Medicine,
Indianapolis. Dr Johnston is now affiliated with Kalamazoo Center for Medical
Studies, Michigan State University, Kalamazoo.
Corresponding author and reprints: Donald P. Orr, MD, Section of
Adolescent Medicine, Department of Pediatrics, Indiana University School of
Medicine, Riley Outpatient Garage, Room 070, 575 N West Dr, Indianapolis,
IN 46202 (e-mail: dporr{at}iupui.edu).
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
|
New sexually transmitted infections among adolescent girls infected with HIV
Trent et al.
Sex. Transm. Infect. 2007;83:468-469.
ABSTRACT
| FULL TEXT
A Review of STD/HIV Preventive Interventions for Adolescents: Sustaining Effects Using an Ecological Approach
DiClemente et al.
J Pediatr Psychol 2007;32:888-906.
ABSTRACT
| FULL TEXT
Burden of Recurrent Chlamydia trachomatis Infections in Young Women: Further Uncovering the "Hidden Epidemic"
Niccolai et al.
Arch Pediatr Adolesc Med 2007;161:246-251.
ABSTRACT
| FULL TEXT
Rifalazil Pretreatment of Mammalian Cell Cultures Prevents Subsequent Chlamydia Infection
Suchland et al.
Antimicrob. Agents Chemother. 2006;50:439-444.
ABSTRACT
| FULL TEXT
Knowledge of sex partner treatment for past bacterial STI and risk of current STI
Niccolai et al.
Sex. Transm. Infect. 2005;81:271-275.
ABSTRACT
| FULL TEXT
Recent trends in HIV and other STIs in the United Kingdom: data to the end of 2002
Brown et al.
Sex. Transm. Infect. 2004;80:159-166.
ABSTRACT
| FULL TEXT
High postpartum rates of sexually transmitted infections among teens: pregnancy as a window of opportunity for prevention
Ickovics et al.
Sex. Transm. Infect. 2003;79:469-473.
ABSTRACT
| FULL TEXT
Gonorrhoea reinfection in heterosexual STD clinic attendees: longitudinal analysis of risks for first reinfection
Mehta et al.
Sex. Transm. Infect. 2003;79:124-128.
ABSTRACT
| FULL TEXT
Adolescence: a time of risk taking
Robinson and Rogstad
Sex. Transm. Infect. 2002;78:314-315.
FULL TEXT
Post-treatment sexual and prevention behaviours of adolescents with sexually transmitted infections
Fortenberry et al.
Sex. Transm. Infect. 2002;78:365-368.
ABSTRACT
| FULL TEXT
|
