This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (9)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Topic Collections  • Bacterial Infections  • Infectious Diseases  • Alert me on articles by topic  Social Bookmarking   What's this?

Gershon S. Segal, MD; James M. Chamberlain, MD

Arch Pediatr Adolesc Med. 2000;154:469-473.

Objective  To measure the increases in resource utilization and hospital charges associated with the evaluation of contaminated blood cultures obtained from emergency department patients at risk for occult bacteremia.

Design  Retrospective medical record review.

Setting  Emergency department of an urban, university-affiliated pediatric referral center.

Patients  Children aged 3 to 36 months with blood cultures positive for bacterial growth obtained between January 1994 and October 1996.

Main Outcome Measures  Increased resource utilization related to contaminated blood culture follow-up, including telephone contact, return emergency department visits, additional diagnostic tests and therapies performed at reevaluation, and hospital admissions. Hospital charges for these additional services were tabulated.

Results  Of 8306 children who had blood cultures drawn, 491 (5.9%) had positive findings. Four hundred eighty-five (98.8%) of these were available for review. Two hundred seventy-six (57%) of 485 were excluded from final analysis. Of the remaining 209 patients at risk for occult bacteremia, 85 (41%) had cultures that grew contaminants only. Follow-up of these 85 patients generated 106 telephone calls, 49 return visits to the emergency department, 102 additional diagnostic tests, 18 doses of parenteral antibiotics, and 12 hospital admissions with a combined length of stay of 24 days. This resulted in additional charges of $78,904, or an additional $642 per true pathogen recovered.

Conclusions  Contaminated blood cultures obtained from children at risk for occult bacteremia lead to substantial increases in resource utilization and hospital charges. These untoward effects should be accounted for in formal decision analyses regarding the management of occult bacteremia.

From the Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, Md (Dr Segal); the George Washington University School of Medicine and Health Sciences, and Children's National Medical Center, Washington, DC (Dr Chamberlain).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Updated Review of Blood Culture Contamination
Hall and Lyman
Clin. Microbiol. Rev. 2006;19:788-802.
ABSTRACT | FULL TEXT  

Retrospective Review of Serious Bacterial Infections in Infants Who Are 0 to 36 Months of Age and Have Influenza A Infection
Smitherman et al.
Pediatrics 2005;115:710-718.
ABSTRACT | FULL TEXT  

Contamination Rates of Blood Cultures Obtained by Dedicated Phlebotomy vs Intravenous Catheter
Norberg et al.
JAMA 2003;289:726-729.
ABSTRACT | FULL TEXT  

Management of Febrile Children in the Age of the Conjugate Pneumococcal Vaccine: A Cost-Effectiveness Analysis
Lee et al.
Pediatrics 2001;108:835-844.
ABSTRACT | FULL TEXT  

Blood Culture Contamination in Occult Bacteremia Work-Ups
JWatch Emergency Med. 2000;2000:12-12.
FULL TEXT