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  Vol. 154 No. 10, October 2000 TABLE OF CONTENTS
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Nebulizer Use in Inner-City Children With Asthma

Morbidity, Medication Use, and Asthma Management Practices

Arlene M. Butz, ScD, RN; Peyton Eggleston, MD; Karen Huss, DNSc, RN, FAAN; Ken Kolodner, PhD; Cynthia Rand, PhD

Arch Pediatr Adolesc Med. 2000;154:984-990.

Objective  To assess the frequency of nebulizer use, describe morbidity and patterns of medication administration, and examine the potential relationships between inhaled anti-inflammatory medication administration, asthma morbidity, and asthma management practices in children with asthma using a nebulizer compared with children with asthma not using a nebulizer.

Research Design  A cross-sectional, descriptive survey of previous events.

Setting  Elementary schools and participants' homes in Baltimore, Md, and Washington, DC.

Participants  Six hundred eighty-six families of children aged 5 to 12 years with a diagnosis of at least mild, persistent asthma.

Interventions  None.

Measurements and Main Results  Asthma morbidity, health care utilization, pattern of asthma medication administration, nebulizer use, and asthma management data were collected by telephone survey administered to caregivers. Nebulizer use was defined as use at least 1 or more days per month during the last 6 months. Of 686 children identified, 231 (33%) reported current nebulizer use. Nebulizer users had significantly increased lifetime hospital admissions, hospitalizations, and emergency department visits in the last 6 months compared with nonnebulizer users. Inhaled corticosteroid administration was low for both groups (nonnebulizer users, 8%; nebulizer users, 15%). In the nebulizer users group, administration of inhaled anti-inflammatory medications was associated with increased asthma morbidity (increased hospitalizations, days and nights with symptoms, and oral steroid use).

Conclusions  Nebulizer use by inner-city children with asthma is higher than anticipated but is not associated with reduced asthma morbidity. This group of high-risk children was undertreated with inhaled corticosteroids for long-term control of asthma despite reports of adequate monitoring by a primary care physician.


From Departments of Pediatrics (Drs Eggleston and Butz) and Pulmonary Medicine (Dr Rand), The Johns Hopkins University School of Medicine, and the School of Nursing (Drs Butz and Huss), and Innovative Medical Research, INC (Dr Kolodner), Baltimore, Md.


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