You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT ARCHIVES
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 151 No. 11, November 1997 TABLE OF CONTENTS
  Archives
  •  Online Features
  ARTICLE
 This Article
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Contact me when this article is cited
 Related Content
 •Similar articles in this journal

Contribution of birth defects and genetic diseases to pediatric hospitalizations. A population-based study

P. W. Yoon, R. S. Olney, M. J. Khoury, W. M. Sappenfield, G. F. Chavez and D. Taylor
Division of Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Ga., USA.

OBJECTIVE: To estimate the contribution of birth defects and genetic diseases to pediatric hospitalizations by use of population-based data. DESIGN: Hospital discharges were categorized according to the diagnostic codes of The International Classification of Diseases, Ninth Revision, Clinical Modification. Hospitalizations that were related to birth defects and genetic diseases were compared with hospitalizations for other reasons, with respect to age, race/ethnicity, sex, length of stay, charges, source of payment, and mortality rate. Hospitalization rates and per capita charges were computed with the use of population estimates from 1990 census data. MATERIALS: The 1991 population-based hospital discharge data from California and South Carolina. RESULTS: Nearly 12% of pediatric hospitalizations in the 2 states combined were related to birth defects and genetic diseases. These children were, on average, about 3 years younger, stayed 3 days longer in a hospital, incurred 184% higher charges, and had a 4 1/2 times greater in-hospital mortality rate than children who were hospitalized for other reasons. The rate of hospitalizations that were related to birth defects and genetic diseases was 4 per 1000 children in both states, but these rates varied by age and race. CONCLUSION: These population-based data are the first contemporary findings to show the substantial morbidity rate and hospitalization charges associated with birth defects and genetic diseases in the pediatric population. IMPLICATIONS: This information is important for planning effective health care strategies, especially as the causes, treatments, and prevention of these disorders are being further elucidated by findings from human genome research and epidemiologic studies.

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Update on Overall Prevalence of Major Birth Defects--Atlanta, Georgia, 1978-2005
JAMA 2008;299:756-758.
FULL TEXT  

Geographic and Occupational Risk Factors for Ventricular Septal Defects: Washington State, 1987-2003
Batra et al.
Arch Pediatr Adolesc Med 2007;161:89-95.
ABSTRACT | FULL TEXT  

Improved National Prevalence Estimates for 18 Selected Major Birth Defects--United States, 1999-2001
JAMA 2006;295:618-620.
FULL TEXT  

Attitudes of Pediatric Residents Toward Ethical Issues Associated With Genetic Testing in Children
Rosen et al.
Pediatrics 2002;110:360-363.
ABSTRACT | FULL TEXT  

Genetic Epidemiology and Congenital Malformations: From the Chromosome to the Crib
Hobbs et al.
Arch Pediatr Adolesc Med 2002;156:315-320.
FULL TEXT  

Deaths Attributed to Pediatric Complex Chronic Conditions: National Trends and Implications for Supportive Care Services
Feudtner et al.
Pediatrics 2001;107:e99-99.
ABSTRACT | FULL TEXT  

Association of Transposition of the Great Arteries in Infants with Maternal Exposures to Herbicides and Rodenticides
Loffredo et al.
Am J Epidemiol 2001;153:529-536.
ABSTRACT | FULL TEXT  

Racial and Temporal Variations in the Prevalence of Heart Defects
Botto et al.
Pediatrics 2001;107:32e-32.
ABSTRACT | FULL TEXT  

Ethical Issues in Genetic Testing of Children
Ross and Moon
Arch Pediatr Adolesc Med 2000;154:873-879.
FULL TEXT  

Pediatric Deaths Attributable to Complex Chronic Conditions: A Population-Based Study of Washington State, 1980-1997
Feudtner et al.
Pediatrics 2000;106:205-209.
ABSTRACT | FULL TEXT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1997 American Medical Association. All Rights Reserved.