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The Rationale for Lowering Serum Cholesterol Levels in American Children
Samuel S. Gidding, MD
Am J Dis Child. 1993;147(4):386-392.
Abstract
• The pediatric approach to the primary prevention of coronary artery disease in adults remains controversial. Measurement and intervention to lower serum cholesterol levels have been advocated recently in a selected group of American children by the Expert Panel on Blood Cholesterol Levels in Children and Adolescents of the National Cholesterol Education Program. This article reviews the clinical and scientific data contributing to the controversy surrounding cholesterol in American children. Arguments in favor of and opposed to an aggressive approach to identifying American children with elevated serum cholesterol levels are presented. The rationale for a selective screening approach is demonstrated.
(AJDC. 1993;147:386-392)
Author Affiliations
From Children's Memorial Hospital, Northwestern University, Chicago, Ill; Department of Pediatrics, University of Michigan, Ann Arbor; and Feinberg Cardiovascular Research Institute, Chicago, Ill.
Footnotes
Accepted for publication November 30, 1992.
Presented in part as the Fourth Annual Patrick John Niland Lecture, Ann Arbor, Mich, March 19, 1991.
Reprint requests to Division of Cardiology #21, Children's Memorial Hospital, 2300 Children's Plaza, Chicago, IL 60614 (Dr Gidding).
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