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The Role of Assisted Ventilation in Survival After Respiratory Failure in Children With AIDS
Douglas L. Abadco, MD;
Madu Rao, MD;
Richard E. Kravath, MD;
Phillip Steiner, MD
Am J Dis Child. 1992;146(9):1052-1055.
Abstract
• Objectives.
—To determine the role of assisted ventilation in children with the acquired immunodeficiency syndrome and acute respiratory failure, and to identify any measurement or variable that predicted survival.
Design.
—Retrospective study.
Setting.
—Kings County (New York) Hospital Center, a tertiary-level inner-city municipal hospital.
Participants.
—Twenty-three children with acquired immunodeficiency syndrome who were endotracheally intubated and mechanically ventilated because of acute respiratory failure.
Measurements/Main Results.
—There were 24 episodes of acute respiratory failure, as one patient survived a first episode and died during the second episode 2 years later. We failed to identify any measurement or variable that predicted survival. During 12 episodes (50%), the patients survived and were weaned from the ventilator.
Conclusions.
—Our findings indicate that a decision to avoid intubation and assisted ventilation in a child with acquired immunodeficiency syndrome and acute respiratory failure should not be made based merely on the presumption of a lethal outcome.
(AJDC. 1992;146:1052-1055)
Author Affiliations
From the Division of Pediatric Pulmonology, Children's Medical Center of Brooklyn, NY.
Footnotes
Accepted for publication December 16, 1991.
Presented in part at the Eastern Society for Pediatric Research, New York, NY, October 20, 1990.
Reprint requests to Department of Pediatrics, Box 49, SUNY Health Science Center at Brooklyn, 450 Clarkson Ave, Brooklyn, NY 11203 (Dr Abadco).
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