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Guadalupe Padilla, MD; M. Gore Ervin, PhD; Michael G. Ross, MD; Rosemary D. Leake, MD

Am J Dis Child. 1991;145(9):991-993.

Abstract
• We measured urine vasopressin (VP) once daily on days 1 through 3 in 18 patients hospitalized with meningitis. Urine VP values were 215±100, 116±44, and 69±23 pg/mL on days 1 through 3, respectively, for children with bacterial meningitis and 34±14, 20±4, and 15±4 pg/mL for those with aseptic meningitis. Urinary VP levels of infants with bacterial meningitis were significantly greater than those of healthy ambulatory subjects (n =18) on all three study days; VP values of infants with bacterial meningitis were also greater than those of infants with aseptic meningitis on study days 2 and 3. The VP levels for the subjects with aseptic meningitis were significantly greater than those of the controls on day 1 only. None of the infants exhibited the clinical syndrome of inappropriate antidiuretic hormone secretion.

(AJDC. 1991;145:991-993)

Author Affiliations
From the Departments of Pediatrics (Drs Padilla and Leake) and Obstetrics (Drs Ervin and Ross), UCLA School of Medicine, Harbor-UCLA Medical Center, Torrance, Calif.

Footnotes
Accepted for publication April 10, 1991.

Reprint requests to Department of Pediatrics, Harbor-UCLA Medical Center, 1000 W Carson St, RB-1, Torrance, CA 90509 (Dr Leake).

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